Injectable Fillers & Biostimulators
Profhilo
Also known as: Profhilo
Pain Level
Mild
Downtime
1-2 days
Results Timeline
Gradual hydration/skin quality changes over weeks
Start Here
First, try this if
Crepey, dehydrated or tired-looking skin. People who do not want filler volume. Mild laxity where skin quality is the main concern. Fitzpatrick III-VI skin tones, with routine injection aftercare.
Don't expect
Results build gradually, not overnight — realistic timeline is Gradual hydration/skin quality changes over weeks.
See a dermatologist first if
Anyone expecting a lifted jawline or major tightening. Active infection or uncontrolled skin inflammation. Patients with unrealistic expectations from one session. Pregnancy/breastfeeding unless medically cleared.
What It Is
Profhilo is a high-concentration injectable hyaluronic acid treatment used for skin quality and bio-remodelling. It is not a classic HA filler because it is not intended to sit as a shaped gel in the face. It spreads through the tissue and is used for hydration, crepiness and mild skin laxity.
Moxie covers it because many people position it as the elegant middle ground between skincare and filler.
How It Works
Profhilo uses stabilized hyaluronic acid complexes that diffuse through tissue. The aim is hydration and dermal remodeling rather than obvious volume. Studies report improvements in firmness, wrinkles and skin quality in selected groups. It should still be treated as an injectable procedure.
The result can be subtle, and it does not replace lifting devices, resurfacing or surgery.
The Evidence
Concerns Addressed
Crepey Skin, Loss of Firmness, Dehydrated Skin, Fine Lines & Wrinkles - via HA-driven hydration and dermal bio-remodelling.
Published studies on Profhilo and HA bio-remodelling report improvements in skin texture, wrinkles and firmness, with good tolerability, but sample sizes and protocols vary. It is best described as a skin-quality injectable, not a structural treatment.
Profhilo (high/low molecular weight stabilized HA) has several published clinical studies including split-face and prospective cohort trials showing measurable skin hydration/elasticity/collagen density improvements (via ultrasound and skin biomechanical testing) at 4-9 weeks. Independent large-scale RCTs are still limited relative to established fillers.
View source →Reviewed by Moxie — last checked July 2026
Am I a Good Candidate?
Crepey, dehydrated or tired-looking skin. People who do not want filler volume. Mild laxity where skin quality is the main concern. Fitzpatrick III-VI skin tones, with routine injection aftercare.
Caution or Avoid
Anyone expecting a lifted jawline or major tightening. Active infection or uncontrolled skin inflammation. Patients with unrealistic expectations from one session. Pregnancy/breastfeeding unless medically cleared.
What to Expect
Step 1 - Consultation: The practitioner checks laxity, hydration and whether HA bio-remodelling is the right category. Step 2 - Numbing: Numbing may be used, though some protocols use a limited number of injection points.
Step 3 - The procedure: Product is injected into selected points where it diffuses through tissue. Step 4 - Immediately after: Small raised bumps can appear temporarily. Avoid heat, sun and heavy exercise as advised.
Step 5 - Timeline and maintenance: Changes build gradually over weeks; many protocols use two sessions and maintenance later.
Cost Breakdown
Personal cost: Not yet available — Moxie has not finalized this figure. UAE market pricing: Not currently available; confirm directly with your clinic. Pricing variables: number of syringes, areas treated and doctor seniority.
Concerns Addressed
Frequently Asked Questions
What's the difference between Profhilo and regular HA filler?
Profhilo is a high-concentration HA that diffuses through tissue rather than sitting as a shaped gel — it's used for hydration and skin bio-remodelling, not for adding volume or structure.
How many Profhilo sessions do you need?
Protocols commonly use two sessions about a month apart, though this should be confirmed with your clinic since exact protocols vary.
Can Profhilo tighten skin like a facelift?
No — evidence suggests some improvement in firmness, but it is not a true lift and does not replace lifting devices, resurfacing or surgery.
The Verdict
Worth Exploring
Tried it.
Moxie Ratings
Not medical advice. Content is based on personal experience and published research. Always consult a qualified dermatologist before starting any new treatment or regimen.
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